Description
Product Characteristics:
Aliases: AW552114 antibody, D14Wsu146e antibody, DKCA3 antibody, MGC94711 antibody, TERF 1 (TRF 1) interacting nuclear factor 2 antibody, TERF 1 interacting nuclear factor 2 antibody, TERF1 (TRF1) interacting nuclear factor 2 antibody, TERF1 interacting nuclear factor 2 antibody, TERF1-interacting nuclear factor 2 antibody, Tin 2 antibody, TIN2 antibody, TINF 2 antibody, Tinf2 antibody, TINF2_HUMAN antibody, TRF 1 interacting nuclear factor 2 antibody, TRF1 interacting nuclear factor 2 antibody, TRF1-interacting nuclear protein 2 antibody
Target Information: This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin\, it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010]